Experiments were conducted from 1996 through 2001 in Georgia, North Carolina, and Texas to determine peanut response to the commercial plant growth regulator Early Harvest® (a commercial mixture of cytokinin, gibberellic acid, and indole butyric acid). Early Harvest (applied in the seed furrow) or Early Harvest TST (applied as a dry seed treatment) followed by four foliar applications (four-leaf peanut, initial pegging, 14 d after initial pegging, and pod fill), was compared to non-treated peanut in five, 13, and three experiments in these respective states. Early Harvest did not affect pod yield or gross economic value of peanut regardless of location, cultivar, or edaphic and environmental conditions. These data suggest that a spray program consisting of Early Harvest most likely will not improve pod yield or gross economic value of peanut.