Field trials were conducted in Georgia, North Carolina, and Texas to evaluate the effects of preplant applications of 2,4-D, dicamba, tribenuron, and tribenuron plus thifensulfuron on peanut yield. Herbicides were applied 30, 15, 7, or 0 d before planting (DBP) in conventional production systems in Georgia and Texas, and 28, 21, 14, 7, and 0 DBP in no- and strip-tillage systems in North Carolina. Amine and ester formulations of 2,4-D did not affect peanut yield at any time of application in any state. Dicamba reduced peanut yield when applied at 0 DBP in two of seven trials. Tribenuron did not affect peanut yield regardless of preplant interval. However, tribenuron plus thifensulfuron reduced yields when applied at 7 DBP in one of five trials. These data suggest that 2,4-D, tribenuron, and tribenuron plus thifensulfuron can be safely used for preplant weed control in peanut when applied 7 DBP. Dicamba should be applied a minimum of 15 DBP.